Radiation Oncology Nomograms

Interactive calculators for practice-shaping radiation oncology prediction models, plus a curated catalog of the field’s most important nomogram families. Every interactive calculator uses exact published coefficients from open-source code repositories, not reverse-engineered graphics.

Models are tiered by buildability: Tier A = exact public engine recovered, Tier B = official calculator or near-exact public materials, Tier C = paper/figure only, Tier D = not reproducible without author code. Only Tier A models have interactive calculators. All others link to their primary publications.

5 interactive calculators 42 models cataloged 10 disease sites 4 evidence tiers

Tier A Exact public engine

Tier B Official calculator available

Tier C Paper / figure only

Tier D Needs author code

Interactive Calculator on this site

Prostate 11 models

Tendulkar 2016 — Salvage RT After Radical Prostatectomy

Interactive Tier A

5-yr & 10-yr freedom from biochemical failure; 5-yr & 10-yr cumulative metastasis

Multi-institutional salvage RT cohort · PMID 27528718 · Source code

Potters 2010 — Post-Brachytherapy Recurrence

Interactive Tier A

7-yr & 9-yr freedom from recurrence after permanent prostate brachytherapy

Includes D90 dosimetric input · PubMed · Source code

Zelefsky 2007 — Pretreatment Biochemical Control (3D-CRT/IMRT)

Interactive Tier A

5-yr & 10-yr recurrence-free probability after definitive 3D-CRT/IMRT

MSKCC cohort, includes RT dose input · PubMed · Source code

Kattan/Zelefsky 2003 — 5-Year Metastasis Risk After 3D-CRT

Interactive Tier A

5-yr probability of metastasis after definitive conformal RT

MSKCC cohort, external validation · PubMed · Source code

Kattan 2000 — Pretreatment EBRT Nomogram

Tier C

5-yr biochemical control after definitive EBRT

Foundational RT nomogram; pre-IMRT/3D-CRT era · PubMed

Kattan 2001 — Brachytherapy Nomogram

Tier C

5-yr freedom from biochemical recurrence after seed brachytherapy

Historical brachy model · PubMed

Stephenson 2007 — Salvage RT (Classic)

Tier C

6-yr progression-free probability after salvage RT

Updated by Tendulkar 2016 · PMC

Meijer 2024 — PSMA-Negative Salvage RT Progression

Tier B

1-yr biochemical progression in PSMA PET/CT-negative salvage RT

PMC · Evidencio

Campbell 2022 — Salvage RT with PSA Kinetics

Tier D

Post-salvage RT progression incorporating PSA kinetics

PubMed

Sabbagh 2024 — ML Distant Metastasis After Salvage RT

Tier D

5-yr distant metastasis (machine learning)

Multi-institutional ML model · Emerging

Mastroleo 2025 — DMFS After Salvage RT

Tier D

5-yr distant metastasis-free survival after salvage RT

Externally validated · Emerging

Head & Neck 8 models

Gross 2008 — Oral Cavity SCC Adjuvant Treatment Decision

Interactive Tier A

5-yr locoregional recurrence-free survival after surgery

Cleveland Clinic cohort · PubMed · Source code

Wang 2013 — Oral Cavity PORT Benefit

Tier C

Locoregional recurrence-free survival with/without postoperative RT

PubMed

Ward 2019 — H&N Reirradiation Severe Late Toxicity

Tier C

Severe late toxicity after modern H&N reirradiation

High value for patient selection · PubMed

Mell 2019 — ω-Score Intensive Treatment Benefit

Tier B

Expected benefit from treatment intensification in locoregionally advanced H&N

Balances cancer risk vs competing mortality · PMC

Sheu 2014 — Symptom Severity During H&N RT

Tier D

Symptom severity prediction during radiation for H&N cancer

PRO-oriented modeling

Zeng 2016 — NPC Long-Term Survival

Tier C

Long-term survival after IMRT for nasopharyngeal carcinoma

Region-specific

Zhang 2018 — T4 NPC Locoregional Relapse

Tier C

Pretreatment LRFS in T4 NPC after IMRT

Subspecialty-specific

Huang 2018 — Elderly/Comorbid NPC Competing-Risk

Tier C

Outcome prediction in elderly/comorbid NPC

Competing-risk framework

Breast 4 models

MSK DCIS Recurrence Nomogram (2010)

Tier B

Local recurrence after lumpectomy for DCIS, with/without RT & endocrine therapy

Foundational breast RT-omission tool · MSK calculator

IBTR! 2.0 (2010)

Tier B

10-yr ipsilateral breast tumor recurrence after BCS with/without WBRT

Overestimates in some cohorts · Evidencio · PMC

Albert 2012 — RT Benefit for Older Women

Tier B

Individualized RT benefit after conservative surgery in older adults

Addresses RT omission · MDA calculator · PubMed

Luo 2019 — PMRT Benefit in T1-2N1

Tier C

Locoregional recurrence risk & PMRT benefit in gray-zone T1-2N1

PubMed

Gynecologic 3 models

Sturdza / Retro-EMBRACE 2021 — Cervical RT/IGABT Survival

Tier C

60-month OS after definitive chemoradiation with image-guided brachytherapy

Most important modern cervical RT nomogram · PubMed

Creutzberg / PORTEC Pooled Nomograms (2015)

Tier B

Recurrence & survival: observation vs pelvic EBRT vs VBT for endometrial cancer

Trial-derived adjuvant model · Calculator · PubMed

Je / KROG 12-08 (2014) — Postop Cervical DM

Tier C

Distant metastasis after postoperative RT for uterine cervical cancer

Second cervical model after Retro-EMBRACE

Rectal / Lower GI 6 models

Valentini 2011 — Pooled-Trial LR / DM / OS Nomograms

Tier B

Local recurrence, distant metastasis, and OS after long-course CRT + surgery

Foundational rectal CRT family (3 endpoints) · PredictCancer · PubMed

van Stiphout 2011/2014 — pCR Prediction (PET/CT)

Tier C

Pathologic complete response using clinical + sequential PET/CT

Organ-preservation logic; requires PET-based inputs

Weiser 2021 — Post-Treatment Surgery Calculator

Tier B

5-yr DFS & OS after multimodal rectal treatment with surgery

Outperformed AJCC & NAR · MSK · JAMA NO

Weiser 2022 — TNT / Watch-and-Wait Calculator

Tier B

Recurrence avoidance after TNT including watch-and-wait

MSK · JAMA NO

Thoracic 2 models

Bradley 2007 — Radiation Pneumonitis

Tier C

Symptomatic radiation pneumonitis risk after thoracic RT

Historical anchor for lung toxicity prediction

Tang 2019 — Severe Acute RP After Postop RT

Tier C

Severe acute radiation pneumonitis after postoperative RT for NSCLC

Niche but useful extension

CNS / Brain Metastases 4 models

Ayala-Peacock 2014/2017 — Distant Brain Failure After SRS

Tier C

Distant brain failure after upfront SRS alone

PMC (2014)

Gorovets 2017 — WBRT-Free Survival After SRS

Tier C

Survival free from salvage WBRT after upfront SRS

Surveillance planning tool

Natarajan 2019 — Intracranial Progression After SRS

Tier C

Time to intracranial progression; informs MRI surveillance cadence

Validated by Carpenter 2022 · PMC

Adjacent: BrainMetGPA, BMV, SINS, TEACHH/Chow

Not nomograms but high-value clinical tools · BrainMetGPA · ePrognosis

Esophagus 1 model

Gabriel 2017 — Neoadjuvant CRT Benefit (Adenocarcinoma)

Tier B

1-yr & 3-yr OS with expected benefit from neoadjuvant chemoradiation

PMC

Bladder 1 model

Necchi 2019 — Locoregional Failure / Adjuvant RT Selection

Tier C

Exclusive locoregional failure after cystectomy; identifies adjuvant RT candidates

Emerging RT nomogram ecosystem

Oligometastatic / SBRT 1 model

METABANK 2019 — Oligometastatic SBRT Survival

Tier C

Overall survival after SBRT/SRS for oligometastatic disease

Adjacent prognostic tool