Potters 2010 Post-Brachytherapy Recurrence Nomogram

Potters 2010 — Post-Brachytherapy Recurrence Prediction

Potters L, Calderone J, Roach M, et al. Postoperative nomogram predicting the 9-year probability of prostate cancer recurrence after permanent prostate brachytherapy using radiation dose as a prognostic variable. Int J Radiat Oncol Biol Phys. 2010;76(4):1061-1065.

Tier A — Exact Public Engine Green badge: Model reproduced from Cleveland Clinic RiskCalc open-source repository

Source: GitHub: riskcalc-website ProstateCancerPredictingPostBrachytherapy/server.R

Endpoints: 7-year and 9-year freedom from recurrence

Training era: Multi-institutional permanent prostate brachytherapy cohort

Clinical T Stage

T1c

T2a

T2b

T2c

Primary Gleason Grade

Secondary Gleason Grade

Isotope

I-125

Pd-103

Adjuvant External Beam Radiotherapy

Yes

D90 (Gy)

Minimum tumor dose covering 90% of prostate volume. Range: 0–280 Gy

Pre-treatment PSA (ng/mL)

Range: 0–100 ng/mL

7-year freedom from recurrence

9-year freedom from recurrence

Technical note: This calculator reproduces the published model coefficients from the Cleveland Clinic RiskCalc open-source repository. The model includes restricted cubic spline transformations for D90 and PSA. The constant block (value=16) is hardcoded from the source R code and reproduced exactly.